Understanding the reactivity of alcohols and hydrocarbons is essential for improving combustion, catalytic systems, and assessing environmental effects. This study focuses on autoignition characteristics of alkanes, alkenes, and alcohols ranging from C₁ − C₃ hydrocarbons and oxygenated fuels including methane (CH₄), ethane (C₂H₆), ethene (C₂H₄), propane (C₃H₈), propene (C₃H₆), methanol (CH₃OH), ethanol (C₂H₅OH), and propanol (C₃H₇OH) at high temperatures. The increased reactivity of ethanol in comparison to ethane and ethene is highlighted by an analysis of reactivity variations in the temperature range of 650 − 1700 K. Between the temperatures of 900 and 1700 K, propane is more reactive than propene due to reaction pathways that promote the synthesis of hydroperoxyl–alkyls rather than aldehydes. Propene is less reactive than propane as it has fewer reaction routes that can produce HȮ₂ than propane at a temperature range of 625−1250 K, unlike ethane and ethene, where ethene is more reactive than ethane. This comparative study sheds light on reactivity disparities of C₁ − C₃ alkane, alkene, and alcohol compounds across different temperature ranges which has not been reported in the available literature.