A NUMERICAL STUDY ON NON-INVASIVE RF-ASSISTED HYPERTHERMIA OF DEEP-SEATED TUMOR
The aim of the present numerical study is to capture the temperature distribution inside the target tissue during RF-assisted hyperthermia of deep-seated tumor. A three-dimensional two-compartment model has been developed in which realistic properties have been assigned for both tissue as well as tumor. The induced electromagnetic heating within the biological tissue has been obtained by solving the simplified Maxwell equation and Pennes bioheat transfer equation utilizing finite element based platform. A cumulative equivalent minutes model (CEM43) has been incorporated to compute the thermal dosage in the computational model. Further, a parametric study has been done to investigate the relative influence of diameter and location of tumor on the temperature distribution and the required thermal dosage during RF-assisted capacitive hyperthermia. The optimal thermal dosage predicted in the numerical study will minimize the damage to the surrounding normal tissue and could play an important role during the treatment planning stage of RF-assisted capacitive hyperthermia.