The present work examines an experimental investigation of thermo-hydraulic performance in Parabolic Trough Collector (PTC) with twisted tape (TT) inserts in the absorber tube for different twist ratios (4.5, 5.5, 6.5, 7.5, 8.5 and 9.5). The experiment is conducted using water as the heat transfer fluid and the Reynolds number ranges from 2210.667 to 4486.996. Nusselt number, friction factor, pressure drop, and instantaneous efficiency for the absorber tube with TT inserts are found comparatively higher than the same results obtained from the plain absorber tube one. To measure the influence of twisted tape on heat transfer enhancement and pressure drop increment, the empirical correlations for the Nusselt number and friction factor have been developed within the above-said range of Reynolds number.