Fluid pumped radiators are widely used to dissipate thermal load from orbiting space capsules to maintain the desired temperature range. Fluid circulated through the heat generating systems are pumped through the space radiator which in turn dissipates energy to deep space. Efficient design of the space radiator is vital for maintaining the required temperatures, meeting the power, mass and volume constraints. Based on the flow path, radiators are classified into series and parallel radiator configurations. As part of the radiator realization for future space missions, experimental studies are carried out in a thermovac chamber to assess the thermal and hydraulic performance of space radiators and compare them for different configurations and working fluids. Perfluoropolyether and Ethylene Glycol Water mixture are used for the present studies. The paper details the experimental schematics for the different studies and the results of the experiments. Series radiator configuration is found to have better thermal performance but lower hydraulic performance than parallel radiator configuration. Working fluids with higher specific heat are found to result in better thermal performance. A configuration which gives optimum performance in terms of thermal performance and pumping power was evolved based on the studies.